zldmЗаводская лаборатория. Диагностика материаловIndustrial laboratory. Diagnostics of materials1028-68612588-0187ООО «Издательство «ТЕСТ-ЗЛ»10.26896/1028-6861-2022-88-4-10-20zldm-1641Research ArticleАНАЛИЗ ВЕЩЕСТВАSUBSTANCES ANALYSISВозможности эксклюзионной хроматографии (в off- и on-line режимах) для снижения матричных влияний при анализе растворов сложного состава методом масс-спектрометрии с индуктивно-связанной плазмойCapabilities of size exclusion chromatography (in off- and on-line modes) to reduce matrix effects in ICP-MS analysis of complex solutionsСерегинаИ. Ф.SereginaI. F.

119991, Москва, Ленинские горы, д. 1, стр. 3

119991, Moscow, Leninskiye Gory, 1–3

sereginairinaf@mail.ruЛебедеваЛ. М.LebedevaL. M.

119991, Москва, Ленинские горы, д. 1, стр. 3

119991, Moscow, Leninskiye Gory, 1–3

ЦюрупаМ. П.TsyurupaM. P.

119334, Москва, ул. Вавилова, д. 28

119334, Moscow, Vavilova ul., 28

ДаванковВ. А.DavankovV. A.

119334, Москва, ул. Вавилова, д. 28

119334, Moscow, Vavilova ul., 28

БольшовМ. А.BolshovM. A.

119991, Москва, Ленинские горы, д. 1, стр. 3142190, Москва, Троицк, ул. Физическая, д. 5

119991, Moscow, Leninskiye Gory, 1–3142190, Moscow, Troitsk, Fizicheskaya ul., 5

Московский государственный университет имени М. В. ЛомоносоваРоссияLomonosov Moscow State UniversityRussian FederationИНЭОС имени А. Н. Несмеянова РАНРоссияA. N. Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of SciencesRussian FederationМосковский государственный университет имени М. В. Ломоносова; Институт спектроскопии РАНРоссияLomonosov Moscow State University; Institute of Spectroscopy of the Russian Academy of SciencesRussian Federation2022270420228841020Copyright © Серегина И.Ф., Лебедева Л.М., Цюрупа М.П., Даванков В.А., Большов М.А., 20222022Серегина И.Ф., Лебедева Л.М., Цюрупа М.П., Даванков В.А., Большов М.А.Seregina I.F., Lebedeva L.M., Tsyurupa M.P., Davankov V.A., Bolshov M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zldm.ru/jour/article/view/1641

В работе изучены аналитические возможности фронтальной эксклюзионной хроматографии с использованием нейтральных полистирольных сорбентов. При исследовании разделения минеральных кислот и их солей установлено, что на микропористых сверхсшитых полистирольных сорбентах Purolite NN-381 и MN-270 происходит четкое отделение зоны ионов тория и редкоземельных элементов от следующей за ней зоны кислоты; ионы высокозарядных элементов (Zr, Hf, Nb, Ta) отделить от кислоты на исследованных сорбентах Purolite не удается. В зоне выхода тория и РЗЭ при их концентрации 0,1 – 50 мкг/л появляются пики существенного самоконцентрирования. Изучены факторы, влияющие на концентрирование аналитов: природа и концентрация кислоты, а также концентрация аналитов влияют на коэффициенты концентрирования, значения которых максимальны в растворах азотной кислоты по сравнению с соляной и фосфорной. На степень концентрирования аналитов влияют структура внутренних пор и дисперсность сорбента, а также скорость пропускания раствора через колонку. Макрокомпоненты морской воды не удерживаются и не концентрируются на сверхсшитом полистироле. Натрий и магний в концентрации 0,1 % масс. не влияют на значение коэффициента концентрирования целевых аналитов. После хроматографического разделения при простом пропускании порции исследуемого раствора через слой сорбента в течение 15 – 30 мин удается получить слабокислые фракции раствора с концентрированными ионами РЗЭ и тория. Полученный концентрат можно вводить непосредственно в масс-спектрометр. Изучена возможность сочетания хроматографического разделения и концентрирования элементов с on-line ИСП-МС детектированием и найдены оптимальные условия детектирования. Правильность разработанного подхода продемонстрирована при определении РЗЭ в морской воде методом добавок.

The analytical capabilities of frontal size exclusion chromatography are studied using neutral polystyrene sorbents. When studying the separation of mineral acids and their salts, it is shown that clear separation of the zone of thorium ions and rare-earth elements from the following acid zone is observed on the microporous hypercrosslinked polystyrene sorbents Purolite NN-381 and MN-270. However, separation of the ions of highly charged elements (Zr, Hf, Nb, Ta) from the acid on the studied Purolite sorbents failed. Peaks of significant self-concentration appear in the zone of thorium and rare-earth element release at a concentration of 0.1 – 50 μg/liter. The factors affecting concentration of the analytes were studied. The nature and concentration of the acid, as well as concentration of the analytes, affect the concentration coefficients which attain maximum values in the solutions of nitric acid compared to hydrochloric and phosphoric acids. The degree of analyte concentration depends on the structure of internal pores and dispersion of the sorbent, as well as on the rate of solution passage through the column. Macro-components of seawater are not retained or concentrated on hypercrosslinked polystyrene. Sodium and magnesium at a concentration of 0.1 wt.% do not affect the value of the concentration factor of the target analytes. After chromatographic separation, weakly acidic fractions of the solution with concentrated ions of REE and thorium can be obtained by simple passing of a portion of the test solution through the sorbent layer for 15 – 30 min. The resulting concentrate can be directly introduced into a mass spectrometer. The possibility of combining chromatographic separation and concentration of elements and on-line ICP-MS detection is studied. Optimal conditions for on-line detection have been selected; the accuracy of the developed approach is demonstrated in the determination of rare earth elements in seawater using the spiked test.

эксклюзионная хроматографияИСП-МСразделение и концентрирование микроэлементовsize exclusion chromatographyICP-MSseparation and preconcentration of microelementsРабота выполнена при финансовой поддержке РФФИ грант 20-03-00354.ReferencesOkina O. I., Lyapunov S. M., Dubenskiy A. S., Erofeeva K. G. An investigation of trace elements’ behavior during chemical preparation of ultramafic matrix rock samples using bomb digestion for analysis by ICP-MS / J. Anal. At. Spectrom. 2020. Vol. 35. P. 2627 – 2638. DOI:10.1039/d0ja00255kOkina O. I., Lyapunov S. M., Dubenskiy A. S., Erofeeva K. G. An investigation of trace elements’ behavior during chemical preparation of ultramafic matrix rock samples using bomb digestion for analysis by ICP-MS / J. Anal. At. Spectrom. 2020. Vol. 35. P. 2627 – 2638. DOI:10.1039/d0ja00255kSun Y., Sun S., Wang C. Y., Xu P. Determination of Rare Earth Elements and Thorium at Nanogram Levels in Ultramafic Samples by Inductively Coupled Plasma-Mass Spectrometry Combined with Chemical Separation and Preconcentration / Geostand. Geoanal. Res. 2013. Vol. 37. P. 65 – 76. DOI:10.1111/j.1751-908X.2012.00174.xSun Y., Sun S., Wang C. Y., Xu P. Determination of Rare Earth Elements and Thorium at Nanogram Levels in Ultramafic Samples by Inductively Coupled Plasma-Mass Spectrometry Combined with Chemical Separation and Preconcentration / Geostand. Geoanal. Res. 2013. Vol. 37. P. 65 – 76. DOI:10.1111/j.1751-908X.2012.00174.xCertificate of Analysis, IAG MUH-1 (Ultramafic rock). International Association of Geoanalysts. 2020. Available at: http://iageo.com/wp-content/uploads/2020/03/M.UH-1-Certificate-of-analysis-revised-4th-November-2016 (accessed 15.12.2021).Certificate of Analysis, IAG MUH-1 (Ultramafic rock). International Association of Geoanalysts. 2020. Available at: http://iageo.com/wp-content/uploads/2020/03/M.UH-1-Certificate-of-analysis-revised-4th-November-2016 (accessed 15.12.2021).Okina O. I., Lyapunov S. M., Dubenskiy A. S. Influence of sample treatment after bomb digestion on determination of trace elements in rock samples by ICP-MS / Microchem. J. 2018. Vol. 140. P. 123 – 128. DOI:10.1016/j.microc.2018.04.020Okina O. I., Lyapunov S. M., Dubenskiy A. S. Influence of sample treatment after bomb digestion on determination of trace elements in rock samples by ICP-MS / Microchem. J. 2018. Vol. 140. P. 123 – 128. DOI:10.1016/j.microc.2018.04.020Li W., Wang C., Gao B., et al. Determination of multielement concentrations at ultra-low levels in alternating magnetite and pyrite by HR-ICP-MS using matrix removal and preconcentration / Microchem. J. 2016. Vol. 127. P. 237 – 246. DOI:10.1016/j.microc.2016.03.018Li W., Wang C., Gao B., et al. Determination of multielement concentrations at ultra-low levels in alternating magnetite and pyrite by HR-ICP-MS using matrix removal and preconcentration / Microchem. J. 2016. Vol. 127. P. 237 – 246. DOI:10.1016/j.microc.2016.03.018Potts P. J., Webb P. C., Thompson M. Bias in the determination of Zr, Y and Rare Earth Element concentrations in selected silicate rocks by ICP-MS when using some routine acid dissolution procedures: evidence from the GeoPT proficiency testing programme / Geostand. Geoanal. Res. 2015. Vol. 39. P. 315 – 327. DOI:10.1111/j.1751-908X.2014.00305.xPotts P. J., Webb P. C., Thompson M. Bias in the determination of Zr, Y and Rare Earth Element concentrations in selected silicate rocks by ICP-MS when using some routine acid dissolution procedures: evidence from the GeoPT proficiency testing programme / Geostand. Geoanal. Res. 2015. Vol. 39. P. 315 – 327. DOI:10.1111/j.1751-908X.2014.00305.xFedyunina N. N., Seregina I. F., Bolshov M. A., et al. Investigation of the efficiency of the sample pretreatment stage for the determination of the Rare Earth Elements in rock samples by inductively coupled plasma mass spectrometry technique / Anal. Chim. Acta. 2012. Vol. 713. P. 97 – 102. DOI:10.1016/j.aca.2011.11.035Fedyunina N. N., Seregina I. F., Bolshov M. A., et al. Investigation of the efficiency of the sample pretreatment stage for the determination of the Rare Earth Elements in rock samples by inductively coupled plasma mass spectrometry technique / Anal. Chim. Acta. 2012. Vol. 713. P. 97 – 102. DOI:10.1016/j.aca.2011.11.035Yu Z., Robinson P., McGoldrick P. An evaluation of methods for the chemical de- composition of geological materials for trace element determination using ICP-MS / Geostand. Newslett. 2001. Vol. 25. P. 199 – 217. DOI:10.1111/j.1751-908X.2001.tb00596.xYu Z., Robinson P., McGoldrick P. An evaluation of methods for the chemical de- composition of geological materials for trace element determination using ICP-MS / Geostand. Newslett. 2001. Vol. 25. P. 199 – 217. DOI:10.1111/j.1751-908X.2001.tb00596.xDubinin A. V. Geochemistry of Rare Earth Elements in the Ocean. — Moscow: Nauka, 2006. — 360 p. [in Russian].Dubinin A. V. Geochemistry of Rare Earth Elements in the Ocean. — Moscow: Nauka, 2006. — 360 p. [in Russian].Tazoe H., Amakawa H., Suzuki K., et al. Determination of Nd isotopic composition in seawater using newly developed solid phase extraction and MC-ICP-MS / Talanta. 2021. Vol. 232. ID 122435. DOI:10.1016/j.talanta.2021.122435Tazoe H., Amakawa H., Suzuki K., et al. Determination of Nd isotopic composition in seawater using newly developed solid phase extraction and MC-ICP-MS / Talanta. 2021. Vol. 232. ID 122435. DOI:10.1016/j.talanta.2021.122435Balaram V. Rare earth elements: a review of applications, occurrence, exploration, analysis, recycling, and environmental impact / Geosci. Front. 2019. Vol. 10. P. 1285 – 1303. DOI:10.1016/j.gsf.2018.12.005Balaram V. Rare earth elements: a review of applications, occurrence, exploration, analysis, recycling, and environmental impact / Geosci. Front. 2019. Vol. 10. P. 1285 – 1303. DOI:10.1016/j.gsf.2018.12.005Hatje V., Bruland K. W., Flegal A. R. Increases in anthropogenic gadolinium anomalies and rare earth element concentrations in San Francisco Bay over a 20 year record / Environ. Sci. Technol. 2016. Vol. 50. P. 4159 – 4168. DOI:10.1021/acs.est.5b04322Hatje V., Bruland K. W., Flegal A. R. Increases in anthropogenic gadolinium anomalies and rare earth element concentrations in San Francisco Bay over a 20 year record / Environ. Sci. Technol. 2016. Vol. 50. P. 4159 – 4168. DOI:10.1021/acs.est.5b04322Klaver G., Verheul M., Bakker I., et al. Anthropogenic rare earth element in rivers: gadolinium and lanthanum. Partitioning between the dissolved and particulate phases in the Rhine River and spatial propagation through the Rhine-Meuse Delta (The Netherlands) / Appl. Geochem. 2014. Vol. 47. P. 186 – 197. DOI:10.1016/j.apgeochem.2014.05.020Klaver G., Verheul M., Bakker I., et al. Anthropogenic rare earth element in rivers: gadolinium and lanthanum. Partitioning between the dissolved and particulate phases in the Rhine River and spatial propagation through the Rhine-Meuse Delta (The Netherlands) / Appl. Geochem. 2014. Vol. 47. P. 186 – 197. DOI:10.1016/j.apgeochem.2014.05.020Bau M., Dulski P. Anthropogenic origin of positive gadolinium anomalies in river waters / Earth Planet Sci. Lett. 1996. Vol. 143. P. 245 – 255. DOI:10.1016/0012-821X(96)00127-6Bau M., Dulski P. Anthropogenic origin of positive gadolinium anomalies in river waters / Earth Planet Sci. Lett. 1996. Vol. 143. P. 245 – 255. DOI:10.1016/0012-821X(96)00127-6Kulaksız S., Bau M. Rare earth elements, Germany: first case of anthropogenic lanthanum as a dissolved microcontaminant in the hydrosphere / Environ. Int. 2011. Vol. 37. P. 973 – 979. DOI:10.1016/j.envint. 2011.02.018Kulaksız S., Bau M. Rare earth elements, Germany: first case of anthropogenic lanthanum as a dissolved microcontaminant in the hydrosphere / Environ. Int. 2011. Vol. 37. P. 973 – 979. DOI:10.1016/j.envint. 2011.02.018Song H., Shin W. J., Ryu J. S., et al. Anthropogenic rare earth elements and their spatial distributions in the Han River, South Korea / Chemosphere. 2017. Vol. 172. P. 155 – 165. DOI:10.1016/j.chemosphere.2016.12.135Song H., Shin W. J., Ryu J. S., et al. Anthropogenic rare earth elements and their spatial distributions in the Han River, South Korea / Chemosphere. 2017. Vol. 172. P. 155 – 165. DOI:10.1016/j.chemosphere.2016.12.135Crocket K. C., Hill E., Abell R. E., et al. Rare earth element distribution in the NE Atlantic: evidence for benthic sources, longevity of the seawater signal, and biogeochemical cycling / Front. Mar. Sci. 2018. Vol. 5. P. 1 – 22. DOI:10.3389/fmars.2018.00147Crocket K. C., Hill E., Abell R. E., et al. Rare earth element distribution in the NE Atlantic: evidence for benthic sources, longevity of the seawater signal, and biogeochemical cycling / Front. Mar. Sci. 2018. Vol. 5. P. 1 – 22. DOI:10.3389/fmars.2018.00147Schmidt K., Bau M., Merschel G., Tepe N. Anthropogenic gadolinium in tap water and in tap water-based beverages fast-food franchises in six major cities in Germany, Sci. Total Environ. 2019. Vol. 687. P. 1401 – 1408. DOI:10.1016/j.scitotenv.2019.07.075Schmidt K., Bau M., Merschel G., Tepe N. Anthropogenic gadolinium in tap water and in tap water-based beverages fast-food franchises in six major cities in Germany, Sci. Total Environ. 2019. Vol. 687. P. 1401 – 1408. DOI:10.1016/j.scitotenv.2019.07.075Hathorne E. C., Frank M., Mohan P. M. Rare earth elements in Andaman Island surface seawater: geochemical tracers for the monsoon / Front. Mar. Sci. 2020. Vol. 767. P. 1 – 19. DOI:10.3389/fmars.2019.00767Hathorne E. C., Frank M., Mohan P. M. Rare earth elements in Andaman Island surface seawater: geochemical tracers for the monsoon / Front. Mar. Sci. 2020. Vol. 767. P. 1 – 19. DOI:10.3389/fmars.2019.00767Hathorne E. C., Stichel T., Brück B., Frank M. Rare earth element distribution in the Atlantic sector of the Southern Ocean: the balance between particle scavenging and vertical supply / Mar. Chem. 2015. Vol. 177. P. 157 – 171. DOI:10.1016/j.marchem.2015.03.011Hathorne E. C., Stichel T., Brück B., Frank M. Rare earth element distribution in the Atlantic sector of the Southern Ocean: the balance between particle scavenging and vertical supply / Mar. Chem. 2015. Vol. 177. P. 157 – 171. DOI:10.1016/j.marchem.2015.03.011Shaw T. J., Duncan T., Schnetger B. A preconcentration/matrix reduction method for the analysis of rare earth elements in seawater and groundwaters by isotope dilution ICP-MS / Anal. Chem. 2003. Vol. 75. P. 3396 – 3403. DOI:10.1021/ac026158eShaw T. J., Duncan T., Schnetger B. A preconcentration/matrix reduction method for the analysis of rare earth elements in seawater and groundwaters by isotope dilution ICP-MS / Anal. Chem. 2003. Vol. 75. P. 3396 – 3403. DOI:10.1021/ac026158eZhu Y., Umemura T., Haraguchi H., et al. Determination of REEs in seawater by ICP-MS after on-line preconcentration using a syringe-driven chelating column / Talanta. 2009. Vol. 78. P. 891 – 895. DOI:10.1016/j.talanta.2008.12.072Zhu Y., Umemura T., Haraguchi H., et al. Determination of REEs in seawater by ICP-MS after on-line preconcentration using a syringe-driven chelating column / Talanta. 2009. Vol. 78. P. 891 – 895. DOI:10.1016/j.talanta.2008.12.072Zhu Y. Determination of rare earth elements in seawater samples by inductively coupled plasma tandem quadrupole mass spectrometry after coprecipitation with magnesium hydroxide / Talanta. 2020. Vol. 209. 120536. DOI:10.1016/j.talanta.2019.120536Zhu Y. Determination of rare earth elements in seawater samples by inductively coupled plasma tandem quadrupole mass spectrometry after coprecipitation with magnesium hydroxide / Talanta. 2020. Vol. 209. 120536. DOI:10.1016/j.talanta.2019.120536Cao X., Yin M., Wang X. Elimination of the spectral interference from polyatomic ions with rare earth elements in inductively coupled plasma mass spectrometry by combining algebraic correction with chromatographic separation / Spectrochim. Acta. Part B. 2001. Vol. 56. P. 431 – 441. DOI:10.1016/S0584-8547(01)00170-7Cao X., Yin M., Wang X. Elimination of the spectral interference from polyatomic ions with rare earth elements in inductively coupled plasma mass spectrometry by combining algebraic correction with chromatographic separation / Spectrochim. Acta. Part B. 2001. Vol. 56. P. 431 – 441. DOI:10.1016/S0584-8547(01)00170-7Freslon N., Bayon G., Birot D., Bollinger C. Determination of rare earth elements and other trace elements (Y, Mn, Co, Cr) in seawater using Tm addition and Mg(OH)2 co-precipitation / Talanta. 2011. Vol. 85. P. 582 – 587. DOI:10.1016/j.talanta.2011.04.023Freslon N., Bayon G., Birot D., Bollinger C. Determination of rare earth elements and other trace elements (Y, Mn, Co, Cr) in seawater using Tm addition and Mg(OH)2 co-precipitation / Talanta. 2011. Vol. 85. P. 582 – 587. DOI:10.1016/j.talanta.2011.04.023Raso M., Censi P., Saiano F. Simultaneous determinations of zirconium, hafnium, yttrium and lanthanides in seawater according to a co-precipitation technique onto iron-hydroxide / Talanta. 2013. Vol. 116. P. 1085 – 1090. DOI:10.1016/j.talanta.2013.08.019Raso M., Censi P., Saiano F. Simultaneous determinations of zirconium, hafnium, yttrium and lanthanides in seawater according to a co-precipitation technique onto iron-hydroxide / Talanta. 2013. Vol. 116. P. 1085 – 1090. DOI:10.1016/j.talanta.2013.08.019Hathorne E. C. Online preconcentration ICP-MS analysis of rare earth elements in seawater / Geochem. Geophy. Geosy. 2012. Vol. 13. N 1. P. 1 – 12. DOI:10.1029/2011GC003907Hathorne E. C. Online preconcentration ICP-MS analysis of rare earth elements in seawater / Geochem. Geophy. Geosy. 2012. Vol. 13. N 1. P. 1 – 12. DOI:10.1029/2011GC003907Seregina I. F., Perevoznik O. A., Bolshov M. A. Acid retardation method in analysis of strongly acidic solutions by inductively coupled plasma mass-spectrometry / Talanta. 2016. Vol. 159. P. 387 – 394. DOI:10.1016/j.talanta.2016.06.056Seregina I. F., Perevoznik O. A., Bolshov M. A. Acid retardation method in analysis of strongly acidic solutions by inductively coupled plasma mass-spectrometry / Talanta. 2016. Vol. 159. P. 387 – 394. DOI:10.1016/j.talanta.2016.06.056Podgornaya E. B., Burova O. I., Radilov A. C., et al. The use of the sorption method of acid retardation in systems with two liquid phases to solve the problems of sample preparation in the ICP-MS analysis system / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 618 – 622 [in Russian].Podgornaya E. B., Burova O. I., Radilov A. C., et al. The use of the sorption method of acid retardation in systems with two liquid phases to solve the problems of sample preparation in the ICP-MS analysis system / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 618 – 622 [in Russian].Khamizov R. Kh., Krachak A. N., Podgornaya E. B., et al. Acid retardation effect in sorption columns with two liquid phases. Capabilities of application to sample preparation in elemental analysis / J. Anal. Chem. 2019. Vol. 74. N 3. P. 186 – 200. DOI:10.1134/S0044450219030071Khamizov R. Kh., Krachak A. N., Podgornaya E. B., et al. Acid retardation effect in sorption columns with two liquid phases. Capabilities of application to sample preparation in elemental analysis / J. Anal. Chem. 2019. Vol. 74. N 3. P. 186 – 200. DOI:10.1134/S0044450219030071Hatch M. J., Dillon J. A. Acid Retardation. A simple physical method for separation of strong acids from their salts / Ind. Eng. Chem. Process Des. Dev. 1963. Vol. 2. N 4. P. 253 – 263. DOI:10.1021/i260008a001Hatch M. J., Dillon J. A. Acid Retardation. A simple physical method for separation of strong acids from their salts / Ind. Eng. Chem. Process Des. Dev. 1963. Vol. 2. N 4. P. 253 – 263. DOI:10.1021/i260008a001Khamizov R. Kh. Sorption method of «acid retardation». Some technological possibilities for electrolyte separation / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 600 – 604 [in Russian].Khamizov R. Kh. Sorption method of «acid retardation». Some technological possibilities for electrolyte separation / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 600 – 604 [in Russian].Krachak A. N., Khamizov R. Kh., Poznukhova V. A. The main regularities of electrolyte separation in the method of acid retardation. Influence of the nature of the cation on the sorption of acids and their salts from binary solutions / Sorbts. Khromatogr. Prots. 2011. Vol. 11. N 1. P. 77 – 88 [in Russian].Krachak A. N., Khamizov R. Kh., Poznukhova V. A. The main regularities of electrolyte separation in the method of acid retardation. Influence of the nature of the cation on the sorption of acids and their salts from binary solutions / Sorbts. Khromatogr. Prots. 2011. Vol. 11. N 1. P. 77 – 88 [in Russian].Tsyurupa M. P., Blinnikova Z. K., Davankov V. A. Ion size exclusion chromatography of mineral electrolytes on neutral nanoporous hypercrosslinked polystyrene: the mechanism of «retardation» of acids, salts and bases / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 541 – 552 [in Russian].Tsyurupa M. P., Blinnikova Z. K., Davankov V. A. Ion size exclusion chromatography of mineral electrolytes on neutral nanoporous hypercrosslinked polystyrene: the mechanism of «retardation» of acids, salts and bases / Sorbts. Khromatogr. Prots. 2013. Vol. 13. N 5. P. 541 – 552 [in Russian].Davankov V. A., Tsyurupa M. P., Alexienko N. N. Selectivity in preparative separations of inorganic electrolytes by size-exclusion chromatography on hypercrosslinked polystyrene and microporous carbons / J. Chromatogr. A. 2005. Vol. 1100. P. 32 – 39. DOI:10.1016/j.chroma.2005.09.007Davankov V. A., Tsyurupa M. P., Alexienko N. N. Selectivity in preparative separations of inorganic electrolytes by size-exclusion chromatography on hypercrosslinked polystyrene and microporous carbons / J. Chromatogr. A. 2005. Vol. 1100. P. 32 – 39. DOI:10.1016/j.chroma.2005.09.007Davankov V. A., Tsyurupa M. P. Preparative frontal size-exclusion chromatography of mineral ions on neutral hypercrosslinked polystyrene / J. Chromatogr. A. 2005. Vol. 1087. P. 3 – 12. DOI:10.1016/j.chroma.2005.02.036Davankov V. A., Tsyurupa M. P. Preparative frontal size-exclusion chromatography of mineral ions on neutral hypercrosslinked polystyrene / J. Chromatogr. A. 2005. Vol. 1087. P. 3 – 12. DOI:10.1016/j.chroma.2005.02.036Davankov V. A., Tsyurupa M. P. Hypercrosslinked Polystyrene Sorbents. Structure, Properties, Application. — Saarbrücken: Palmarium Academic Publishing, 2012. — 76 p. [in Russian].Davankov V. A., Tsyurupa M. P. Hypercrosslinked Polystyrene Sorbents. Structure, Properties, Application. — Saarbrücken: Palmarium Academic Publishing, 2012. — 76 p. [in Russian].Ohtaki H., Radnai T. Structure and dynamics of hydrated ions / Chem. Rev. 1993. Vol. 93. N 3. P. 1157 – 1204. DOI:10.1021/cr00019a014Ohtaki H., Radnai T. Structure and dynamics of hydrated ions / Chem. Rev. 1993. Vol. 93. N 3. P. 1157 – 1204. DOI:10.1021/cr00019a014Nightingale E. R. Phenomenological Theory of Ion Solvation. Effective Radii of Hydrated Ions / Phys. Chem. 1959. Vol. 63. N 9. P. 1381 – 1387. DOI:10.1021/j150579a011Nightingale E. R. Phenomenological Theory of Ion Solvation. Effective Radii of Hydrated Ions / Phys. Chem. 1959. Vol. 63. N 9. P. 1381 – 1387. DOI:10.1021/j150579a011Davankov V. A., Tsyurupa M. P., Blinnikova Z. K., Pavlova L. A. Self-concentration effect in preparative SEC of mineral electrolytes using nanoporous neutral polymeric sorbents / J. Sep. Sci. 2009. Vol. 32. P. 64 – 73. DOI:10.1002/jssc.200800449Davankov V. A., Tsyurupa M. P., Blinnikova Z. K., Pavlova L. A. Self-concentration effect in preparative SEC of mineral electrolytes using nanoporous neutral polymeric sorbents / J. Sep. Sci. 2009. Vol. 32. P. 64 – 73. DOI:10.1002/jssc.200800449Tsyurupa M., Blinnikova Z., Davankov V. Ion Size Exclusion Chromatography on Hypercrosslinked Polystyrene Sorbents as a Green Technology of Separating Mineral Electrolytes / Inamuddin D., Mohammed A. (eds.) Green Chromatographic Techniques. — Dordrecht: Springer, 2014. P. 19 – 54. DOI:10.1007/978-94-007-7735-4 2Tsyurupa M., Blinnikova Z., Davankov V. Ion Size Exclusion Chromatography on Hypercrosslinked Polystyrene Sorbents as a Green Technology of Separating Mineral Electrolytes / Inamuddin D., Mohammed A. (eds.) Green Chromatographic Techniques. — Dordrecht: Springer, 2014. P. 19 – 54. DOI:10.1007/978-94-007-7735-4 2

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