zldmЗаводская лаборатория. Диагностика материаловIndustrial laboratory. Diagnostics of materials1028-68612588-0187ООО «Издательство «ТЕСТ-ЗЛ»10.26896/1028-6861-2024-90-6-23-26zldm-2225Research ArticleАНАЛИЗ ВЕЩЕСТВАSUBSTANCES ANALYSISОпределение лития и кальция в новых материалах для остеопластики на основе гидроксиапатитов методом эмиссионной фотометрии пламениQuantification of lithium and calcium in novel hydroxyapatite-based materials for osteoplasty using flame photometryФоминаА. А.FominaA. A.

Алла Алексеевна Фомина,

119334, Москва, Ленинский просп., д. 49.

Alla A. Fomina,

49, Leninsky prosp., Moscow, 119334.

ДеминаА. Ю.Demina,A. Yu.

Анна Юрьевна Демина,

119334, Москва, Ленинский просп., д. 49.

Anna Yu. Demina,

49, Leninsky prosp., Moscow, 119334.

АндрееваН. А.AndreevaN. A.

Надежда Александровна Андреева,

119334, Москва, Ленинский просп., д. 49.

Nadezhda A. Andreeva,

49, Leninsky prosp., Moscow, 119334.

ПенкинаТ. Н.PenkinaT. N.

Татьяна Николаевна Пенкина,

119334, Москва, Ленинский просп., д. 49.

Tatiyana N. Penkina,

49, Leninsky prosp., Moscow, 119334.

ПетраковаН. В.PetrakovaN. V.

Наталия Валерьевна Петракова,

119334, Москва, Ленинский просп., д. 49.

 

Nataliya V. Petrakova,

49, Leninsky prosp., Moscow, 119334.

ФилатоваД. Г.FilatovaD. G.

Дарья Геннадьевна Филатова,

119991, Москва, Ленинские горы, д. 1, стр. 3.

Dariya G. Filatova,

1-3, Leninskiye Gory, Moscow, 119991.

gak1.analyt@gmail.comИнститут металлургии и материаловедения им. А. А. Байкова Российской академии наукРоссияBaikov Institute of Metallurgy and Materials Science of the Russian Academy of SciencesRussian FederationМосковский государственный университет имени М. В. Ломоносова, химический факультетРоссияLomonosov Moscow State UniversityRussian Federation2024210620249062326Copyright © Фомина А.А., Демина А.Ю., Андреева Н.А., Пенкина Т.Н., Петракова Н.В., Филатова Д.Г., 20242024Фомина А.А., Демина А.Ю., Андреева Н.А., Пенкина Т.Н., Петракова Н.В., Филатова Д.Г.Fomina A.A., Demina, A.Y., Andreeva N.A., Penkina T.N., Petrakova N.V., Filatova D.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zldm.ru/jour/article/view/2225

Предложена методика определения добавок лития и компонента основы пробы — кальция при синтезе новых материалов на основе гидроксиапатитов (ГА) методом эмиссионной фотометрии пламени для установления связи «условия синтеза — состав — функциональные свойства». Образцы керамики получены методом совместного осаждения с использованием карбоната лития и прокаливанием при 1300 °C. Синтезировали материалы с содержанием лития от 0,25 до 1 % ат., часть образцов — с добавлением от 0,25 до 1 % ат. церия (Ce(NO3)3). Для определения лития в образцах ГА использовали метод добавок и адекватные растворы сравнения. Кальций определяли в отдельных аликвотах после разбавления в 50 раз. Показано, что определение лития на уровне концентраций 0,1 мг/л методом фотометрии пламени в растворах гидроксиапатитов возможно с Sr 0,1. Установлено, что допировать материал литием методом совместного осаждения из растворов затруднительно, при этом термическая обработка в процессе синтеза не влияет на результат. Предложено использовать совместное допирование материала литием и церием, при этом не менее 0,25 % ат. Li включается в структуру ГА. Разработанная методика может быть использована для определения лития и кальция с применением пламенного фотометра ПФА-378 на всех этапах синтеза новых материалов на основе ГА.

A method for quantification of lithium additives and calcium as a sample base component during synthesis of new materials based on hydroxyapatites (HA) using flame atomic emission spectroscopy is proposed to reveal a connection in the chain «synthesis conditions — composition — functional properties». Ceramic samples were obtained by co-deposition using Li carbonate and calcination at 1300°C. The materials were synthesized with a lithium content of 0.25 to 1 at.%, some of the samples were synthesized with the co-addition of cerium Ce(NO3)3 from 0.25 to 1 at.%. The method of additives and reference solutions were used to determine Li in HA samples. The determination of calcium was carried out in separate aliquots after 50-fold dilution. It is shown that the determination of lithium at concentrations of 0.1 mg/liter by flame photometry in hydroxyapatite solutions is possible with Sr of 0.1. It is shown that it is difficult to dope the material with lithium by co-precipitation from solutions, while heat treatment during synthesis does not affect the result. It is proposed to use joint doping of the material with lithium and cerium, while at least 0.25 at.% Li is included in the HA structure. The developed technique can be used to determine lithium and calcium using a flame photometer PFA 378 at all stages of the synthesis of new materials based on HA.

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The authors declare that there are no conflicts of interest present.