DETERMINATION OF PHTHALATES IN MILK, DAIRY PRODUCTS, WATER, JUICES AND BEVERAGES USING ULTRAHIGH LIQUID PERFORMANCE CHROMATOGRAPHY/QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY OF HIGH RESOLUTION

The widespread use of polyethylene terephthalate packaging (PET) in the food market can be a threat to the  health of people.  In the  process of manufacturing these polymeric materials, various substances are used that improve the properties of the finished package. In particular, phthalates are considered to be one of these dangerous pollutants because their molecules are  not  chemically attached to polymer chains, these substances can  easily  pass  from  plastic containers to food, beverages and  water during packaging or production processes. The study was carried out by ultrahighperfomance liquid  chromatography with  a tandem quadrupole-time-of-flight mass  spectrometric high-resolution detector. The concentrations of phthalates was  varies widely  in  foodstuffs purchased  in  food  market, diisooctyl phthalate has been  found  in the  highest concentration in almost every category of specimens studied. The same  phthalic acid ester proved to be the  most  common, followed by dibutyl phthalate, diisobutyl phthalate and diethyl phthalate. The ranges of detectable contents for phthalates were 15 – 3000 ng/ml (R² > 0,99). Limit of detection were from 0.5 to 15 ng/ml.  The relative standard deviation of the  analysis results did not exceed 15%.

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