ЭКСПРЕССНОЕ ОПРЕДЕЛЕНИЕ НИЗКИХ СОДЕРЖАНИЙ МЕТИЛФОСФОНОВОЙ КИСЛОТЫ МЕТОДОМ ВЭЖХ-МС/МС

Разработан экспрессный подход к определению метилфосфоновой кислоты (МФК) - конечного продукта гидролиза нервнопаралитических отравляющих веществ в водных объектах - методом жидкостной хроматографии - тандемной масс-спектрометрии. Выбраны оптимальные условия хроматографического разделения и масс-спектрометрического детектирования. Разработанный способ характеризуется хорошей чувствительностью, точностью, селективностью определения, отсутствием мешающего влияния компонентов основы пробы при анализе природных вод. Способ был опробован при определении МФК в различных реальных водных объектах методом «введено - найдено». При прямом ВЭЖХ-МС/МС определении предел обнаружения МФК в водных объектах составил 10 нг/мл.

продукты трансформации нервнопаралитических отравляющих веществ, метилфосфоновая кислота, ВЭЖХ-МС/МС, анализ воды, products of nerve agent hydrolysis, methylphosphonic acid, HPLC-MS/MS, water analysis

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