New metal-affinity sorbents based on thin films of lanthanide stearates

New metal-affinity sorbents based on lanthanide stearates have been developed, characterized and studied in the «laboratory on target» format. In the course of the Langmuir method, adapted to the hemispherical surface of the droplet, 13 new sorbents were formed on the surface of the target for matrix-activated laser desorption/ionization mass spectrometry (MALDI), representing collapsed thin films (monolayers) of cerium, praseodymium, neodymium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium and lutetium stearates. The methods of optical microscopy, scanning electron microscopy, and atomic force microscopy have shown that spots of a material with a developed surface are formed on the target. Using MALDI MS, it was determined that the main structural unit is a metal distearate with one labile valence. All structures exhibit specificity towards chlorine-containing adducts, which confirms their metal-affinity properties. When conducting metal-affinity extraction in the «laboratory on target» format, sorbents based on ytterbium, thulium, erbium, gadolinium, neodymium, and cerium stearates exhibit the most pronounced metal-affinity properties, a good level of specificity and selectivity. Gadolinium stearate-based structures can be attributed to universal metal-affinity sorbents that have great prospects in bioorganic analysis. Metal-affinity sorbents containing neodymium, praseodymium, gadolinium, dysprosium, holmium, thulium and lutetium have been investigated and described for the first time.

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