The use of technical substances of anticoagulant rodenticides in the input control, analysis of products and evaluation samples in the framework of comparative tests

An overview of the information indicated in the passports of reference materials (RM) or certified reference materials (CRM) from the world’s leading manufacturers for the substances of anticoagulant rodenticides of the 4-hydroxycoumarin series is presented. Most of the characteristics in the passports are presented without taking into account uncertainties and specifying the methods by which the values given were obtained, which does not allow researchers to unambiguously assess the validity of the substance, and the quantity of the standard sample does not allow the consumer to reproduce at least some of these characteristics. As an alternative, the use of technical substances for the analysis of rodenticidal product products is considered. The stages of the input control procedure are proposed as part of the supplier assessment, which would take into account the specifics of the substances under consideration (tautomeric transformations, polymorphism, and rich isomeric composition). Using the example of the dif-nakum substance, the nonequivalence of the spectral characteristics of cis/trans isomers is demonstrated, which must be taken into account when using spectrophotometric or fluorimetric detectors. It is noted that the determination of the isomeric ratio is an important characteristic of the substance and is indicated in the passports for technical substances, but not in the documentation for standards, and this limits the use of the additive method in the analytical determination of the substance. It is proposed to provide the ISI testers with a sample of the technical substance from which the test sample was prepared, indicating in the research assignment the concentration range and the possible range of substances used. In this case, the participants of the ICI have the opportunity to carry out a full-fledged entrance control, confirm the authenticity of the substance, and then quantify its content in the assessment sample. The information provided is of interest both to manufacturers of rodenticide products and to potential providers of interlaboratory benchmarking tests, manufacturers of standard samples of pesticides and laboratories engaged in the analysis of products in the field of «pest control».

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